Continuing the global fight against Symantec Endpoint Protection 🙂 here is a possible way to ensure that old virus definitions are not staying on the C drive.
First of all we need to temporarily turn the Tamper Protection off for the whole environment. It can be done from the SEP Manager console for a particular group. Go to Clients view, on the left hand side you will see a list of groups. Select your target group and then on the right hand side select Policies tab: